文章摘要
| 易剑峰,熊印华,贾红伟.中药杏香兔耳风对大鼠宫颈粘膜EGF表达的影响[J].江西中医药大学学报,2007,(2):72-73. |
| 中药杏香兔耳风对大鼠宫颈粘膜EGF表达的影响 |
| The Effect of Ainsliaea Fragrans Champ on EGF Levels of Cervix Mucosae of Rats |
| 投稿时间：2006-12-26 修订日期：2006-12-26 |
| DOI： |
| 中文关键词: 杏香兔耳风,宫颈炎,EGF |
| 英文关键词: Ainsliaea fragrans Champ,cervicitis,EGF |
| 基金项目: |
| 易剑峰,熊印华,贾红伟 |
| [1]宜春学院,宜春336006 [2]江西科技师范学院,南昌330006 [3]中国中医科学院基础理论研究所,北京100000 |
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| 中文摘要: |
| 目的探讨中药杏香兔耳风治疗宫颈炎的作用机理.方法建立大鼠宫颈炎动物模型,分别于给药4天、10天后观察杏香兔耳风不同剂量组对大鼠宫颈粘膜表皮生长因子(EGF)表达的影响,并进行病理组织学检查.结果杏香兔耳风高、中剂量组对苯酚胶浆造成的实验性大鼠宫颈炎模型,给药4天后,可明显升高宫颈粘膜EGF表达,与模型对照组比较具有显著性差异(其中高剂量组P＜0.01,中剂量组P＜0.05);给药10天后,各组宫颈粘膜EGF表达无明显差异;病理组织学检查结果也表明,杏香兔耳风高、中剂量组对大鼠宫颈炎有一定的治疗作用,以高剂 |
| 英文摘要: |
| objective:to study the mechanism of Ainsliaea fragrans Champ treated cervicitis.Method: Establish the model of cervicitis by hydroxybenzene mucilage in rats.After 4 and 10 days,observe the effect of Ainsliaea fragrans Champ on EGF expressed of cervix mucosae of rats of different dose group,and analyzed its pathomorphology.Results: Comparing with model group,Ainsliaea fragrans Champ high dose group and middle dose group can significantly heighten the EGF levels of rat cervix mucosae after 4 days.after 10 days,the EGF levels of all groups have no significant difference.on the other hand,by histopathologic examination we can find Ainsliaea fragrans Champ high dose group and middle dose group could improve rat cervicitis,and high dose group has more significant therapeutic effect.Conclusion: Ainsliaea fragrans Champ's therapeutic effect has a relation with its raising EGF express of earlier period in rat cervix mucosae. |
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