文章摘要
| 蔡忠明,刘彦廷.定眩胶囊对椎-基底动脉供血不足大鼠脑组织SOD活性和血清NO含量的影响[J].江西中医药大学学报,2007,(3):66-67. |
| 定眩胶囊对椎-基底动脉供血不足大鼠脑组织SOD活性和血清NO含量的影响 |
| The Effect of Dingxuan Capsule to the Activity of Brain Tissue SOD and the Content of Serum NO of Vertebro - basilar Artery Insufficiency Rat |
| 投稿时间：2007-01-10 修订日期：2007-01-10 |
| DOI： |
| 中文关键词: 定眩胶囊 痰浊中阻 椎-基底动脉供血不足 |
| 英文关键词: Dingxuan Capsule; Stagnation of phlegm - damp in middle - jiao; Vertebro - Basilar Artery Insufficiency |
| 基金项目: |
| 蔡忠明,刘彦廷 |
| 江苏省扬州市中医院神经内科,扬州225000 |
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| 中文摘要: |
| 目的：观察定眩胶囊对椎-基底动脉供血不足大鼠脑组织SOD活性和血清NO含量的影响。方法：60只SD大鼠随机分为6组,分别为假手术组、模型组、西比灵组和定眩胶囊高、中、低剂量组,除假手术组外均进行中医痰浊中阻和西医椎动脉受压双重模型造模,并给予相应治疗药物,比较治疗后各组大鼠脑组织SOD活性和血清NO含量。结果：定眩胶囊大、中剂量组脑组织SOD活性和血清NO含量均较模型组高,P均〈0.05。结论：定眩胶囊可提高椎-基底动脉供血不足大鼠脑组织SOD活性和血清NO含量。 |
| 英文摘要: |
| Objective:To observe the effect of Dingxuan Capsule to the activity of brain tissue SOD and the content of serum NO of vertebro-basilar artery insufficiency rat.Methods:Sixty SD rat were random divided to 6 group,that were sham operated group,model group,Flunarizine group and Dingxuan Capsule high,middle and low dose group.Except the sham operated group,making the model of stagnation of turbid phlegm in middle-Jiao of TCM and compression of vertebral artery,every group were given corresponding drug,and comparing the activity of brain tissue SOD and the content of serum NO.Results:The activity of brain tissue SOD and the content of Dingxuan Capsule high and middle dose group were higher than model group,P<0.05.Conclusion:Dingxuan Capsule can raise the activity of brain tissue SOD and the content of serum NO of vertebro-basilar artery insufficiency rat. |
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