文章摘要
| 邱剑锋,李国栋,肖诚,李国峰,舒涛,$2,洪子夫.养血润肠方对小鼠血虚型慢性功能性便秘结肠组织匀浆及血清中NO的影响[J].江西中医药大学学报,2007,(3):68-69. |
| 养血润肠方对小鼠血虚型慢性功能性便秘结肠组织匀浆及血清中NO的影响 |
| The Affection of Yangxuerunchang Formula on the NO in Colonic Homogenate and Serum of Blood-deficiency type Chronic Functionality Constipation Mice |
| 投稿时间：2007-01-09 修订日期：2007-01-09 |
| DOI： |
| 中文关键词: 一氧化氮 慢性功能性便秘 养血润肠方 中药 |
| 英文关键词: Nitrogen Monoxidum; Chronic Functionality Constipation ; Yangxuerunchang Formula~ Traditional Chinese Medicine |
| 基金项目: |
| 邱剑锋,李国栋,肖诚,李国峰,舒涛,$2,洪子夫 |
| [1]中国中医科学院广安门医院肛肠科,北京100053 [2]中日友好医院临床研究部,北京100029 |
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| 中文摘要: |
| 目的：研究养血润肠方对小鼠血虚型慢性功能性便秘结肠组织匀浆及血清中NO的影响。方法：取健康小鼠72只,随机分为6组,正常对照组、模型组灌服生理盐水,乳果糖组和养血润肠方小、中、大剂量组分别给予乳果糖口服液和养血润肠方不同剂量灌胃。各组动物灌服药物14天后,处死,检测大鼠结肠匀浆及血清中NO的含量。结果：养血润肠方各剂量组结肠匀浆NO含量均较模型组低,P〈0.05;乳果糖组与模型组无显著性差异,P〉0.05。养血润肠方各剂量组与乳果糖均可降低便秘小鼠血清中NO含量,养血润肠方大剂量组优于乳果糖组。结论：养血 |
| 英文摘要: |
| Objective:Research on the affection of Yangxuerunchang formula(YXRCF) to the content of NO in Colonic Homogenate and Serum of Blood-deficiency type Chronic Functionality Constipation Mice.Methods:Choose 72 healthy mice and divided into six groups randomly.Normal group and model group were given normal sodium,lactulose oral solution (LOS) group and YXRCF low,middle,high-dose group were given lactulose oral solution and different dose YXRCF.The period of intragastic infusing is two weeks.Results:The NO in colonic homogenate : YXRCF can decrease the content of NO,but LOS can't.The NO in serum :Both YXRCF and LOL can decrease the content of NO.Conclusion:YXRCF can decrease the content of NO in colonic homogenate and serum of Blood-deficiency type Chronic Functionality Constipation Mice. |
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