文章摘要
黄敬耀,涂秀英,闵江,黄芳华,夏春华.冠心生脉颗粒抗心肌缺血药理实验研究[J].江西中医药大学学报,2007,(3):70-72. |
冠心生脉颗粒抗心肌缺血药理实验研究 |
Pharmacological Experiment of Guanxinshengmai Granule on Anti-myocardial Ischemia |
投稿时间:2006-07-17 修订日期:2006-07-17 |
DOI: |
中文关键词: 冠心生脉颗粒 心肌缺血 在体心外膜心电图 心肌梗死 犬 |
英文关键词: Guanxinshengmai granule; Myocardial Ischemia; Epicardium electrocardiogram in vivo; Myocardial infarct; Dog |
基金项目: |
黄敬耀,涂秀英,闵江,黄芳华,夏春华 |
江西中医学院药理教研室,南昌330006 |
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中文摘要: |
目的:研究冠心生脉颗粒抗心肌缺血缺氧的药理作用。方法:观察在体心外膜心电图ST段抬高总数及其ST段抬高的总点数变化,采用定量组织学N-BT染色法,用落点求积法和重量求积法,以求得梗死面积和梗死重量的百分率。结果:冠心生脉颗粒能明显减少犬因心肌缺血而引起的ST段抬高及其ST段抬高的总点数,有效降低心肌缺血后梗死面积和梗死区的百分率。结论:冠心生脉颗粒具有明显增加缺血区心肌供血供氧,减轻心肌梗死程度,缩小心肌梗死范围,对冠心病有良好的防治作用。 |
英文摘要: |
Objective:To observe the pharmacological effect of Guanxinshengmai granule on anti-myocardial ischemia and anoxic.Methods:To observe the sum of the raised ST segment and raised ST segment dot number in vivo epicardium electrocardiogram,adopting the method of ration histology N-BT dyeing,using fall point planimetry and weight planimetry to calculate the infarct size and percentage of infarct weight.Results:Guanxinshengmai granule can reduce the dog's raised ST segment and raised ST segment dot number obviously,and reduce the area of infarct and the percentage of the section of infarct efficiency.Conclusion:Guanxinshengmai granule can increase the oxygen supply of ischemic myocardium area,alleviate the degree of myocardial infarct,reduce the area of myocardial infarct,it has better effect on prevention an cure the coronary heart disease. |
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