文章摘要
| 万红娇,杨翠萍,王敏璋.自拟抗弓形虫汤对急性弓形虫感染小鼠SOD、MDA的影响[J].江西中医药大学学报,2007,(4):61-63. |
| 自拟抗弓形虫汤对急性弓形虫感染小鼠SOD、MDA的影响 |
| The Effect of Kanggongxingchong decoction on SOD and MDA in Mice Infected with Toxoplsma Gondii |
| 投稿时间：2007-03-15 修订日期：2007-03-15 |
| DOI： |
| 中文关键词: 自拟抗弓形虫汤,刚地弓形虫,超氧化物歧化酶,丙二醛 |
| 英文关键词: Kanggongxingchong Decoction,Toxoplasma gondii,SOD,MDA |
| 基金项目:江西省自然科学基金资助项目(0340008) |
| 万红娇,杨翠萍,王敏璋 |
| 江西中医学院基础医学院 南昌330006 |
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| 中文摘要: |
| 目的探讨自拟抗弓形虫汤对急性弓形虫感染小鼠血浆、心、肝、肺超氧化物歧化酶(SOD)和丙二醛(MDA)含量的影响.方法昆明小鼠80只,随机分为抗弓形虫汤组(灌胃自拟抗弓形虫汤)、复方SMZ组(灌胃复方SMZ)、模型组和正常组,每组20只.用RH株弓形虫建立小鼠模型,观察小鼠发病及存活时间,血浆、心、肝、肺SOD活性和MDA含量.结果自拟抗弓形虫汤能推迟弓形虫感染小鼠的发病时间,延长弓形虫感染小鼠的生存时间;可明显提高小鼠SOD活性,同时降低MDA含量.与复方SMZ组比较,差异有显著性(P＜0.05).结论自 |
| 英文摘要: |
| Objective:To investigate the effect of Kanggongxingchong decoction(KGXCT)on SOD and MDA in mice infected with Toxoplasma gondii.Methods:Eighty Mice were divided into KGXCT group(intragastric administration KGXCT),Compound SMZ group(intragastric administration compound SMZ),Model group,Normal group.The mice model was made by RH toxoplsma gondii,SOD activities and the content of MDA in mice serum,heart,liver and lung were detected.Rusults:KGXCT group can delay the invasion time of mice infected by toxoplsma gondii,and their life were extend.When it came to the comparison of the activity of SOD and the content of MDA in each group of mice's serum,heart,liver and lung,the Normal group and model group had remarkable difference(P<0.05).Conclusion:KGXCT can increase greatly the quality of life,and can anti-oxidation injury in mice infected with Toxoplasma gondii. |
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